THE STARTING POINT

Whereyouare.

Tired, depleted, not yourself — and told your labs are “normal.” At the Breen Center, normal isn't the goal. Optimal is. Your journey begins by being truly seen.

Our Approach

A new standard of care. 

The Breen Center for Optimal Health is a forward-thinking integrative health and wellness practice. Our mission is simple and uncompromising: to give you back your health and your life through education, empowerment, lifestyle optimization and evidence-based medicine.

Whole-person

Functional & integrative — we treat the system, not the symptom.

Known well

You aren't a number in our practice and we get to know you well.

Evidence-based

Modalities vetted against stringent standards for consistent, optimal outcomes.

Optimization is personal.

The Proven Process

Five steps to optimal health.

Step 01 · Comprehensive biomarker panels

Advanced Labs

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Questions about the journey? Mia, our AI concierge, has answers.Talk to Mia now

See the journey

One minute inside  optimal health. 

From your first labs to a life lived fully — the five-step path, in motion.

BREEN · JOURNEY FILM

Hormone Optimization

Your hormones,  brought into balance. 

Testosterone, thyroid, DHEA, sermorelin and growth hormone for men; menopause, peri-menopause, PCOS, osteoporosis and thyroid care for women — optimized to how you should feel, not just a lab “normal.”

  • Testosterone & HGH
  • Menopause care
  • Thyroid
  • DHEA
  • Sermorelin

Hover a node to explore

Tap a marker to explore

Executive Health Physical

See what a standard  physical misses. 

A comprehensive screen — carotid ultrasound (CIMT), EKG, arterial-disease analysis, bone density, visceral fat, body composition, sleep study and metabolic rate, reviewed with you by Dr. Breen.

Tap the markers on the screen →

Cardiovascular & Cognitive

Protect the heart.  Sharpen the mind. 

arterial rhythm · live trace
BaleDoneen Method™

Cardiovascular wellness

A science-based, personalized medical approach designed to detect, prevent, and reverse cardiovascular disease. By shifting focus from standard "risk factor" assessments to direct "disease treatment," it aims to identify arterial plaque and extinguish inflammation before a heart attack or stroke occurs.

foggy pathway clear cognition
Bredesen Protocol™

Brain wellness

A comprehensive, personalized protocol targeting the upstream drivers of cognitive decline — to support clarity, memory and long-term brain health.

The Wellness Lab

An integrative center for  cellular renewal. 

Built for preventive health, longevity, and a longer health span.

Red & near-infrared light, dosed for cellular recharge.

Photobiomodulation

ReGen Pod — PBM

A red and near-infrared bed delivering the optimal light-therapy dosage to revitalize cellular energy, ease pain and inflammation, increase circulation, and promote tissue regeneration.

High/low oxygen contrast floods tissues with oxygen-rich blood.

Oxygen training

LiveO2 — Adaptive Contrast

A training system that introduces high and low oxygen levels to create a short-term hypoxic state, flooding damaged and inflamed tissues with oxygen-rich blood.

Electromagnetic pulses help cells recharge and self-regulate.

Pulsed electromagnetic field

Pulse — PEMF

Electromagnetic energy that helps cells recharge — increasing cellular energy to complement nutrition and fitness and support the body's natural healing and regulating abilities.

Regenerative & Lifestyle

Built around  your biology. 

“As the premier practice for optimizing health, we offer a variety of services and programs to meet your needs.”

Regenerative

Male Sexual Health

Advanced, evidence-based regenerative options including GAINSWave acoustic-wave therapy and Platelet-Rich Plasma (PRP).

  • GAINSWave™
  • PRP therapy
  • Personalized care
Lifestyle

Nutrition & Medical Weight Loss

One-on-one coaching, body-composition analysis, personalized nutrition plans, macronutrient optimization and supplement support.

  • 1:1 coaching
  • Personalized plans
  • Macro guidance
Functional Medicine

Functional & Integrative Care

Food-allergy testing, low-dose naltrexone, toxin burden testing, digestive health and genetic testing (MTHFR / APO-E) — root-cause medicine.

  • Food-allergy testing
  • Toxin burden testing
  • Genetic testing
Not sure which is right for you?Ask Mia now

Dr. Sean Breen, D.O.

The Physician

Medicine that  knows your name. 

Dr. Sean Breen is a board-certified physician and is internationally recognized as a leading expert in Bioidentical Hormone Replacement Therapy (BHRT) for both men and women. Dr. Breen has been a pioneer in hormone therapy for decades. Long before it was widely accepted, he recognized what the evidence already showed: that thoughtfully prescribed hormones could dramatically improve — and even save — the lives of patients navigating menopause and andropause. He was practicing this medicine when few others would, and time has proven him right.

What sets Dr. Breen apart isn't only his expertise — it's the way he practices. He takes the time to truly listen, to understand each patient as a whole person rather than a list of symptoms, and to build the kind of relationship that real, lasting health requires. Patients consistently describe feeling genuinely seen and heard, often for the first time in their medical journey.

A proud veteran, Dr. Breen served nearly a decade as a Naval medical officer and battalion surgeon, both stateside and overseas during his deployment in Iraq in support of U.S. Marines. He was awarded the Navy and Marine Corps Achievement Medal with Valor for his service.

Dr. Breen is happily married to the love of his life, Erin, and together they have been blessed with three wonderful children. They reside in Orange County, California.

Board Certified

BHRT Expert

Naval Veteran

Battalion Surgeon

3,000

patients served

16+ years

in practice

ASK MIA

Mia · AI Health Concierge · Live

Have a question?Ask Mia anything.

Mia is the Breen Center's AI concierge, trained on everything here — the 5-step journey, our services, the Wellness Lab, and what to expect on your first visit. Tap the avatar, allow your mic, and ask anything you'd ask the front desk.

  • “Walk me through the 5-step journey.”
  • “What happens at my first executive physical?”
  • “Can Mia help with hormones, energy, or weight?”
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Mia · Breen Center for Optimal Health Live

Visit · Irvine, CA

Your health optimization  starts here. 

Location17910 Sky Park Circle, Suite 109 Irvine, CA 92614
Phone(877) 721-0047
Emailinfo@breencenter.com
HoursMon–Thu 8:30a–5:00p · Fri 8:30a–4:00p Sat–Sun closed

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