Male Sexual Health
Advanced, evidence-based regenerative options including GAINSWave acoustic-wave therapy and Platelet-Rich Plasma (PRP).
- GAINSWave™
- PRP therapy
- Personalized care
Tired, depleted, not yourself — and told your labs are “normal.” At the Breen Center, normal isn't the goal. Optimal is. Your journey begins by being truly seen.
Our Approach
The Breen Center for Optimal Health is a forward-thinking integrative health and wellness practice. Our mission is simple and uncompromising: to give you back your health and your life through education, empowerment, lifestyle optimization and evidence-based medicine.
Functional & integrative — we treat the system, not the symptom.
You aren't a number in our practice and we get to know you well.
Modalities vetted against stringent standards for consistent, optimal outcomes.
Optimization is personal.
The Proven Process
Comprehensive bloodwork and biomarker panels — the data foundation that looks far beyond a standard physical.
See the journey
From your first labs to a life lived fully — the five-step path, in motion.
Hormone Optimization
Testosterone, thyroid, DHEA, sermorelin and growth hormone for men; menopause, peri-menopause, PCOS, osteoporosis and thyroid care for women — optimized to how you should feel, not just a lab “normal.”
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Executive Health Physical
A comprehensive screen — carotid ultrasound (CIMT), EKG, arterial-disease analysis, bone density, visceral fat, body composition, sleep study and metabolic rate, reviewed with you by Dr. Breen.
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Cardiovascular & Cognitive
A science-based, personalized medical approach designed to detect, prevent, and reverse cardiovascular disease. By shifting focus from standard "risk factor" assessments to direct "disease treatment," it aims to identify arterial plaque and extinguish inflammation before a heart attack or stroke occurs.
A comprehensive, personalized protocol targeting the upstream drivers of cognitive decline — to support clarity, memory and long-term brain health.
The Wellness Lab
Built for preventive health, longevity, and a longer health span.
Red & near-infrared light, dosed for cellular recharge.
A red and near-infrared bed delivering the optimal light-therapy dosage to revitalize cellular energy, ease pain and inflammation, increase circulation, and promote tissue regeneration.
High/low oxygen contrast floods tissues with oxygen-rich blood.
A training system that introduces high and low oxygen levels to create a short-term hypoxic state, flooding damaged and inflamed tissues with oxygen-rich blood.
Electromagnetic pulses help cells recharge and self-regulate.
Electromagnetic energy that helps cells recharge — increasing cellular energy to complement nutrition and fitness and support the body's natural healing and regulating abilities.
Regenerative & Lifestyle
“As the premier practice for optimizing health, we offer a variety of services and programs to meet your needs.”
Advanced, evidence-based regenerative options including GAINSWave acoustic-wave therapy and Platelet-Rich Plasma (PRP).
One-on-one coaching, body-composition analysis, personalized nutrition plans, macronutrient optimization and supplement support.
Food-allergy testing, low-dose naltrexone, toxin burden testing, digestive health and genetic testing (MTHFR / APO-E) — root-cause medicine.
Dr. Sean Breen, D.O.
The Physician
Dr. Sean Breen is a board-certified physician and is internationally recognized as a leading expert in Bioidentical Hormone Replacement Therapy (BHRT) for both men and women. Dr. Breen has been a pioneer in hormone therapy for decades. Long before it was widely accepted, he recognized what the evidence already showed: that thoughtfully prescribed hormones could dramatically improve — and even save — the lives of patients navigating menopause and andropause. He was practicing this medicine when few others would, and time has proven him right.
What sets Dr. Breen apart isn't only his expertise — it's the way he practices. He takes the time to truly listen, to understand each patient as a whole person rather than a list of symptoms, and to build the kind of relationship that real, lasting health requires. Patients consistently describe feeling genuinely seen and heard, often for the first time in their medical journey.
A proud veteran, Dr. Breen served nearly a decade as a Naval medical officer and battalion surgeon, both stateside and overseas during his deployment in Iraq in support of U.S. Marines. He was awarded the Navy and Marine Corps Achievement Medal with Valor for his service.
Dr. Breen is happily married to the love of his life, Erin, and together they have been blessed with three wonderful children. They reside in Orange County, California.
Board Certified
BHRT Expert
Naval Veteran
Battalion Surgeon
3,000
patients served
16+ years
in practice
Mia · AI Health Concierge · Live
Mia is the Breen Center's AI concierge, trained on everything here — the 5-step journey, our services, the Wellness Lab, and what to expect on your first visit. Tap the avatar, allow your mic, and ask anything you'd ask the front desk.
Visit · Irvine, CA
Tell us a little about yourself — the office will reach out to schedule your visit.